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Mutationalprocessesof tobacco smokingand APOBECactivitygenerate protein-truncating mutations incancergenomes

Published
11/03/2023
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Authors: Nina Adler, Alexander T. Bahcheli, Kevin C. L. Cheng, Khalid N. Al-Zahrani, Mykhaylo Slobodyanyuk, Diogo Pellegrina, Daniel Schramek, Jüri Reimand

Cancer is driven by a few mutations that enable oncogenic properties of cells; This study found that smoking commercial tobacco is associated with changes to DNA that make cancers harder to treat.

 

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