In the complicated and unpredictable context of the COVID-19 epidemic, substance users are facing a lot of problems, not only physically, but also mentally and especially difficulty accessing medical services. These factors easily trigger the relapse or overdose of drugs, leading to severe consequences for themselves, for their family and for the society. Therefore, VHATTC – Uiversity of Medicine and Pharmacy in Ho Chi Minh city organized a sharing session on “RELAPSE PREVENTION AND HARM REDUCTION STRATEGIES DURING COVID-19 PANDEMIC” to provide some information and preventive methods, contributing to minimize unwanted consequences caused by drug use.